Portsmouth is an independent city in Virginia southwest and across the Elizabeth River from Norfolk. As of the 2010 census, the population was 95,535. It is part of the Hampton Roads metropolitan area. The Norfolk Naval Shipyard and Naval Medical Center Portsmouth are historic and active U.S. Navy facilities located in Portsmouth.

Norfolk ( (listen) NOR-fuuk) is an independent city in the Commonwealth of Virginia in the United States. At the 2020 census, the population was 238,005, making it the third-most populous city in Virginia after neighboring Virginia Beach and Chesapeake, and the 91st-largest city in the nation. The city was incorporated in 1705 and is one of the oldest cities in the Hampton Roads metropolitan area, and is considered to be the historic, urban, financial, and cultural center of the region. Norfolk is at the core of the metropolitan area, surrounding the Hampton Roads natural harbor at the mouth of the Chesapeake Bay. It is one of nine cities and seven counties that constitute the Hampton Roads metro area, officially known as the Virginia Beach-Norfolk-Newport News, VA-NC MSA. The city is bordered to the west by the Elizabeth River and to the north by the Chesapeake Bay. It also shares land borders with the independent cities of Chesapeake to its south and Virginia Beach to its east. As the city is bordered by multiple bodies of water, Norfolk has many miles of riverfront and bayfront property, including beaches on the Chesapeake Bay. The coastal zones are important for the economy. The largest naval base in the world, Naval Station Norfolk, is located in Norfolk along with one of NATO's two Strategic Command headquarters. Additionally Norfolk is an important contributor to the Port of Virginia. It is home to Maersk Line, Limited, which manages the world's largest fleet of US-flag vessels. However, this low-lying coastal infrastructure is also very vulnerable to sea level rise, with water levels expected to rise by more than 5.5 feet by the end of the 21st century. The city has a long history as a strategic military and transportation point, where many railroad lines started. It is linked to its neighbors by an extensive network of interstate highways, bridges, tunnels, and three bridge-tunnel complexes.

Suffolk is an independent city in the Commonwealth of Virginia, and as such has no county. As of the 2010 census, the population was 84,585. It is the largest city in Virginia by boundary land area as well as the 14th largest in the country. Suffolk is located in the Hampton Roads metropolitan area. This also includes the independent cities of Chesapeake, Hampton, Newport News, Norfolk, Portsmouth, and Virginia Beach, and smaller cities, counties, and towns of Hampton Roads. With miles of waterfront property on the Nansemond and James rivers, present-day Suffolk was formed in 1974 after consolidating with Nansemond County and the towns of Holland and Whaleyville. The current mayor (as of 2021) is Mike Duman.

Virginia Beach is an independent city located on the southeastern coast of the Commonwealth of Virginia in the United States. The population was 459,470 as of the 2020 census. Although mostly suburban in character, it is the most populous city in Virginia and the 43rd-most populous city in the nation. Located on the Atlantic Ocean at the mouth of the Chesapeake Bay, Virginia Beach is the largest city in the Hampton Roads metropolitan area. This area, known as "America's First Region", also includes the independent cities of Chesapeake, Hampton, Newport News, Norfolk, Portsmouth, and Suffolk, as well as other smaller cities, counties, and towns of Hampton Roads. Virginia Beach is a resort city with miles of beaches and hundreds of hotels, motels, and restaurants along its oceanfront. Every year the city hosts the East Coast Surfing Championships as well as the North American Sand Soccer Championship, a beach soccer tournament. It is also home to several state parks, several long-protected beach areas, military bases, a number of large corporations, Virginia Wesleyan University and Regent University, the international headquarters and site of the television broadcast studios for Pat Robertson's Christian Broadcasting Network (CBN), Edgar Cayce's Association for Research and Enlightenment, and numerous historic sites. Near the point where the Chesapeake Bay and the Atlantic Ocean meet, Cape Henry was the site of the first landing of the English colonists, who eventually settled in Jamestown, on April 26, 1607. The city is listed in the Guinness Book of Records as having the longest pleasure beach in the world. It is located at the southern end of the Chesapeake Bay Bridge-Tunnel, which was the world's longest bridge-tunnel complex until the Hong Kong-Zhuhai-Macau Bridge opened in 2018.